Lifetime Impact of Achondroplasia Study in Europe-LIAISE (LIAISE) / 欧州での軟骨無形成症患者の生涯の影響に関する研究(LIAISE)


It was posted the titled “Lifetime Impact of Achondroplasia Study in Europe-LIAISE” on 28th Feb. at “” which is a database of privately and publicly funded clinical studies conducted around the world. The duration of the study is for December 2017 – April 2019. The main outcome measure will be healthcare resource use.

The tentative translation and the original disclosure document of its excerption are as follows.




  • 臨床的負担
  • 医療リソースの使用
  • 社会経済的負担
  • 心理社会的負担


Brief Summary:

Observational study looking at the burden of illness in achondroplasia subjects aged 5-70. The study will include a 5 year review of historical clinical data as well as a single point collection of questionnaire data to look at the impact on the following in individuals with achondroplasia versus a normative population:

  • Quality of life
  • Clinical burden
  • Healthcare resource use
  • Socio-economic burden
  • Psychosocial burden

Up to 300 subjects will be included in sites in Germany, Spain, Italy, Sweden and Denmark